The COVID-19 pandemic is one of the most serious global challenges to delivering affordable and equitable treatment to children with cancer we have witnessed in the last few decades. This Special Report aims to summarise general principles for continuing multi-disciplinary care during the SARS-CoV-2 (COVID-19) pandemic. With contributions from the leadership of the International Society for Paediatric Oncology (SIOP), Children’s Oncology Group (COG), St Jude Global programme and Childhood Cancer International, we have sought to provide a framework for healthcare teams caring for children with cancer during the pandemic. We anticipate the burden will fall particularly heavily on children, their families and cancer services in low- and middleincome countries. Therefore, we have brought together the relevant clinical leads from SIOPEurope, COG and SIOP-PODC (Pediatric Oncology in Developing Countries) to focus on the six most curable cancers that are part of the WHO Global Initiative in Childhood Cancer. We provide some practical advice for adapting diagnostic and treatment protocols for children with cancer during the pandemic, the measures taken to contain it (e.g. extreme social distancing) and how to prepare for the anticipated recovery period.
The paper can be found here.
Wilms Tumor (WT) or nephroblastoma is a highly curable childhood cancer with cure rates around 90% as shown by the SIOP Renal Tumour Study Group (SIOP-RTSG) and the Children’s Oncology Group (COG) (1). During the last decades treatment is stratified according to clinical (SIOP and COG) and molecular risk factors (COG) to avoid under- and overtreatment. This resulted in curing patients by minimizing acute toxicities and late effects and in avoiding as many relapses as possible. To provide this standard of care will be a specific challenge during the COVID-19 pandemic as the ability to deliver adequate diagnosis, treatment and supportive care for patients with WT will vary from country to country and even from region to region depending on the overload of the health care system caused by COVID-19.